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Pseudomyxoma Peritonei (PMP): Expert Guidance for a Rare Cancer Journey
Clear, compassionate support for patients facing CRS and HIPEC
What is PMP?
Pseudomyxoma Peritonei (PMP) is a rare type of cancer that develops in the abdominal cavity (the peritoneum). It most commonly begins in the appendix, although it can also originate in the ovaries or other abdominal organs.
Instead of forming a solid tumor that spreads through the bloodstream, PMP produces a thick, jelly-like substance called mucin. Over time, this mucin accumulates inside the abdomen, coating organs such as the intestines, liver, and spleen.
Because PMP grows slowly in most cases, it can go undetected for years. Symptoms are often vague and may include:
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Increasing abdominal size or bloating
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Abdominal pain or pressure
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Changes in bowel habits
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Hernias
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Ovarian masses in women
PMP is rare, affecting approximately 1-3 people per million each year. Because of its rarity, many patients struggle to find providers experienced in treating it.
Treatment
Cytoreductive Surgery
(CRS)
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CRS is an extensive abdominal surgery in which a specialized surgical oncologist removes all visible tumor and mucin from the abdominal cavity.
This may include:
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Removal of the appendix
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Removal of portions of the peritoneal liningCRS can last 8 - 12+ hours and requires significant recovery time.
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Resection of parts of affected organs (such as sections of bowel)
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Omentectomy (removal of fatty abdominal tissue)
The goal of CRS is "complete cytoreduction", meaning no visible disease remains.
This surgery can last 8 - 12+ hours and requires significant recovery time.
HIPEC
(Hyperthermic Intraperitoneal Chemotherapy)
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Following CRS, many patients receive Hyperthermic Intraperitoneal Chemotherapy (HIPEC).
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During HIPEC:
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Heated chemotherapy is circulated throughout the abdominal cavity
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The chemotherapy bath lasts 60 - 120 minutes
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The heat enhances the effectiveness of the chemotherapy
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The treatment targets microscopic cancer cells remaining after surgery
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Unlike traditional IV administered chemotherapy, HIPEC is delivered into the abdomen, which allows for higher local concentrations with reduced systemic exposure.
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HIPEC is typically performed during the same operations as CRS.
Looking For Support?
At Guided Path, our primary focus is on individuals and families facing a PMP cancer diagnosis. However, we believe that no one touched by cancer should ever feel overlooked or unsupported. If we are not equipped to meet your specific needs, we will work alongside you to connect you with trusted community resources—and we’ll follow up to ensure you’re receiving the care and assistance you deserve.
While many of those we serve come through referrals from healthcare providers, we welcome direct contact from any cancer patient, caregiver, or family member seeking support. No formal referral is needed—just a need for support and a willingness to let us walk alongside you.
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Phone: 423-438-3799 | E-mail: info@guidedpathtcs.org
Guided Path TCS
Located in Mooresburg, TN.
Serving east Tennessee.
(423) 438 - 3799
Hours
Mon 9:00am - 5:00pm est
Tue 9:00am - 5:00pm est
Wed 9:00am - 5:00pm est
Thu 9:00am - 5:00pm est
Fri 9:00am - 5:00pm est
Sat appointment only
Sun closed
Contact Us
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